Chocolate Keto Collagen Protein

$29.99

Keywords: Weight Loss and Maintenance,Ketosis, Lean Muscle Mass, Blood Sugar Support, Healthy Joints, Skin, Nails and Hair

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Description

Keywords: Weight Loss and Maintenance, Body Fat, Lean Mass, Blood Sugar Support, Healthy Joints, Skin, Nails and Hair

KETOSIS TO SUPPORT WEIGHT MANAGEMENT

Keto Collagen Diet is a functional food in the sense that it has the potential to offer health benefits beyond the traditional concept of food; nutrition and energy (1). Ketones are derived from fats. The ketones in TET METABOLIC’s Keto Collagen Formula are derived from Medium Chain Triglycerides (MCTs), from coconut. During long periods of fasting (2, 3) and intense exercise (4), when there is insufficient glucose to provide the energy substrate for the cells, ketones are produced from fats, by the liver (ketogenesis), increasing the blood ketone levels (ketonemia) to support the energy needs of the body. Thus, essentially during this state of ketosis body fat is “burned”. Such knowledge about the shuffling of energy substrates and utilization during these periods of higher energy need is what serves as the model of nutritional ketosis. During the dietary intake of ketones and little or no carbohydrate, nutritional ketosis is generated which changes the metabolic profile of the normal body. With Keto collagen diet, there is decreased storage of fat, enhanced fat oxidation (burning) while the feeling of hunger is suppressed (satiety) (5-7) and has been used as a weight management diet (7, 8).

KETOSIS, BEYOND FAT BURN
Ketone reduces oxidative stress as it suppresses mitochondrial production of Reactive Oxygen Species (ROS) (9, 10). Oxidative stress drives most chronic health challenges (11, 12). During nutritional ketosis just as in prolonged fasting and intense exercise, blood sugar is kept at physiologic low levels (13, 14) and as such has been suggested as a diet for the control of blood glucose overload (8, 15). It is worth noting that physiologic and nutritional ketosis is different from diabetic ketoacidosis, a pathologic condition (8, 16, 17). During physiologic and nutritional ketosis, the ketones are rapidly used and blood pH remains normal, unlike the pathologic ketoacidosis where the acidic ketones accumulate and blood pH falls, becoming acidic (8).

COLLAGEN SUPPORTS BODY STRUCTURE

The collagen in TET METABOLIC’s Keto Collagen Formula is sourced from grass-fed, pasture-raised cows. Collagen is the most abundant protein in the body, and it is reported to comprise of ~ 30% of the entire protein content of the body (18). There are different types of collagen performing different functions in the body, including helping to maintain tissue’s integrity (18). It is found in a host of tissues, including the bone, joints, skin and blood vessels (18). The collagen in our Keto Collagen Formula helps to maintain muscle mass during the Keto-based weight loss (19, 20). It also supports bone and joint health (21, 22). Additionally, the collagen improves skin elasticity (23) and supports the reduction of skin cellulite during long-term use (>6months) (24).

References

1. Hasler CM. Functional foods: benefits, concerns and challenges-a position paper from the american council on science and health. J Nutr. 2002;132(12):3772-81.

2. Cahill GF, Jr. Starvation in man. Clin Endocrinol Metab. 1976;5(2):397-415.

3. Cahill GF, Jr. Starvation in man. N Engl J Med. 1970;282(12):668-75.

4. Koeslag JH, Noakes TD, Sloan AW. Post-exercise ketosis. J Physiol. 1980;301:79-90.

5. Paoli A, Bosco G, Camporesi EM, Mangar D. Ketosis, ketogenic diet and food intake control: a complex relationship. Front Psychol. 2015;6:27.

6. Gibson AA, Seimon RV, Lee CM, Ayre J, Franklin J, Markovic TP, et al. Do ketogenic diets really suppress appetite? A systematic review and meta-analysis. Obes Rev. 2015;16(1):64-76.

7. Bueno NB, de Melo IS, de Oliveira SL, da Rocha Ataide T. Very-low-carbohydrate ketogenic diet v. low-fat diet for long-term weight loss: a meta-analysis of randomised controlled trials. Br J Nutr. 2013;110(7):1178-87.

8. Paoli A, Rubini A, Volek JS, Grimaldi KA. Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets. Eur J Clin Nutr. 2013;67(8):789-96.

9. Maalouf M, Sullivan PG, Davis L, Kim DY, Rho JM. Ketones inhibit mitochondrial production of reactive oxygen species production following glutamate excitotoxicity by increasing NADH oxidation. Neuroscience. 2007;145(1):256-64.

10. Shimazu T, Hirschey MD, Newman J, He W, Shirakawa K, Le Moan N, et al. Suppression of oxidative stress by beta-hydroxybutyrate, an endogenous histone deacetylase inhibitor. Science. 2013;339(6116):211-4.

11. Furukawa S, Fujita T, Shimabukuro M, Iwaki M, Yamada Y, Nakajima Y, et al. Increased oxidative stress in obesity and its impact on metabolic syndrome. J Clin Invest. 2004;114(12):1752-61.

12. Holvoet P. Relations between metabolic syndrome, oxidative stress and inflammation and cardiovascular disease. Verh K Acad Geneeskd Belg. 2008;70(3):193-219.

13. Stubbs BJ, Cox PJ, Evans RD, Santer P, Miller JJ, Faull OK, et al. On the Metabolism of Exogenous Ketones in Humans. Front Physiol. 2017;8:848.

14. Kesl SL, Poff AM, Ward NP, Fiorelli TN, Ari C, Van Putten AJ, et al. Effects of exogenous ketone supplementation on blood ketone, glucose, triglyceride, and lipoprotein levels in Sprague-Dawley rats. Nutr Metab (Lond). 2016;13:9.

15. Feinman RD, Pogozelski WK, Astrup A, Bernstein RK, Fine EJ, Westman EC, et al. Dietary carbohydrate restriction as the first approach in diabetes management: critical review and evidence base. Nutrition. 2015;31(1):1-13.

16. Krebs HA. The regulation of the release of ketone bodies by the liver. Adv Enzyme Regul. 1966;4:339-54.

17. Cahill GF, Jr. Fuel metabolism in starvation. Annu Rev Nutr. 2006;26:1-22.

18. Di Lullo GA, Sweeney SM, Korkko J, Ala-Kokko L, San Antonio JD. Mapping the ligand-binding sites and disease-associated mutations on the most abundant protein in the human, type I collagen. J Biol Chem. 2002;277(6):4223-31.

19. Kitakaze T, Sakamoto T, Kitano T, Inoue N, Sugihara F, Harada N, et al. The collagen derived dipeptide hydroxyprolyl-glycine promotes C2C12 myoblast differentiation and myotube hypertrophy. Biochem Biophys Res Commun. 2016;478(3):1292-7.

20. Zdzieblik D, Oesser S, Baumstark MW, Gollhofer A, Konig D. Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcopenic men: a randomised controlled trial. Br J Nutr. 2015;114(8):1237-45.

21. Bruyere O, Zegels B, Leonori L, Rabenda V, Janssen A, Bourges C, et al. Effect of collagen hydrolysate in articular pain: a 6-month randomized, double-blind, placebo controlled study. Complement Ther Med. 2012;20(3):124-30.

22. Konig D, Oesser S, Scharla S, Zdzieblik D, Gollhofer A. Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women-A Randomized Controlled Study. Nutrients. 2018;10(1).

23. Proksch E, Segger D, Degwert J, Schunck M, Zague V, Oesser S. Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin Pharmacol Physiol. 2014;27(1):47-55.

24. Schunck M, Zague V, Oesser S, Proksch E. Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology. J Med Food. 2015;18(12):1340-8.

Product Information

Keywords: Weight Loss and Maintenance, Ketosis, Lean Muscle Mass, Blood Sugar, Joints, Skin, Nails and Hair

Supplement Fact

Product Literature

KETOSIS TO SUPPORT WEIGHT MANAGEMENT
Keto Collagen Diet is a functional food in the sense that it has the potential to offer health benefits beyond the traditional concept of food; nutrition and energy (1). Ketones are derived from fats. The ketones in TET METABOLIC’s Keto Collagen Formula are derived from Medium Chain Triglycerides (MCTs), from coconut. During long periods of fasting (2, 3) and intense exercise (4), when there is insufficient glucose to provide the energy substrate for the cells, ketones are produced from fats, by the liver (ketogenesis), increasing the blood ketone levels (ketonemia) to support the energy needs of the body. Thus, essentially during this state of ketosis body fat is “burned”. Such knowledge about the shuffling of energy substrates and utilization during these periods of higher energy need is what serves as the model of nutritional ketosis. During the dietary intake of ketones and little or no carbohydrate, nutritional ketosis is generated which changes the metabolic profile of the normal body. With Keto collagen diet, there is decreased storage of fat, enhanced fat oxidation (burning) while the feeling of hunger is suppressed (satiety) (5-7) and has been used as a weight management diet (7, 8).

KETOSIS, BEYOND FAT BURN
Ketone reduces oxidative stress as it suppresses mitochondrial production of Reactive Oxygen Species (ROS) (9, 10). Oxidative stress drives most chronic health challenges (11, 12). During nutritional ketosis just as in prolonged fasting and intense exercise, blood sugar is kept at physiologic low levels (13, 14) and as such has been suggested as a diet for the control of blood glucose overload (8, 15). It is worth noting that physiologic and nutritional ketosis is different from diabetic ketoacidosis, a pathologic condition (8, 16, 17). During physiologic and nutritional ketosis, the ketones are rapidly used and blood pH remains normal, unlike the pathologic ketoacidosis where the acidic ketones accumulate and blood pH falls, becoming acidic (8).

COLLAGEN SUPPORTS BODY STRUCTURE
The collagen in TET METABOLIC’s Keto Collagen Formula is sourced from grass-fed, pasture-raised cows. Collagen is the most abundant protein in the body, and it is reported to comprise of ~ 30% of the entire protein content of the body (18). There are different types of collagen performing different functions in the body, including helping to maintain tissue’s integrity (18). It is found in a host of tissues, including the bone, joints, skin and blood vessels (18). The collagen in our Keto Collagen Formula helps to maintain muscle mass during the Keto-based weight loss (19, 20). It also supports bone and joint health (21, 22). Additionally, the collagen improves skin elasticity (23) and supports the reduction of skin cellulite during long-term use (>6months) (24).

References
1. Hasler CM. Functional foods: benefits, concerns and challenges-a position paper from the american council on science and health. J Nutr. 2002;132(12):3772-81.

2. Cahill GF, Jr. Starvation in man. Clin Endocrinol Metab. 1976;5(2):397-415.

3. Cahill GF, Jr. Starvation in man. N Engl J Med. 1970;282(12):668-75.

4. Koeslag JH, Noakes TD, Sloan AW. Post-exercise ketosis. J Physiol. 1980;301:79-90.

5. Paoli A, Bosco G, Camporesi EM, Mangar D. Ketosis, ketogenic diet and food intake control: a complex relationship. Front Psychol. 2015;6:27.

6. Gibson AA, Seimon RV, Lee CM, Ayre J, Franklin J, Markovic TP, et al. Do ketogenic diets really suppress appetite? A systematic review and meta-analysis. Obes Rev. 2015;16(1):64-76.

7. Bueno NB, de Melo IS, de Oliveira SL, da Rocha Ataide T. Very-low-carbohydrate ketogenic diet v. low-fat diet for long-term weight loss: a meta-analysis of randomised controlled trials. Br J Nutr. 2013;110(7):1178-87.

8. Paoli A, Rubini A, Volek JS, Grimaldi KA. Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets. Eur J Clin Nutr. 2013;67(8):789-96.

9. Maalouf M, Sullivan PG, Davis L, Kim DY, Rho JM. Ketones inhibit mitochondrial production of reactive oxygen species production following glutamate excitotoxicity by increasing NADH oxidation. Neuroscience. 2007;145(1):256-64.

10. Shimazu T, Hirschey MD, Newman J, He W, Shirakawa K, Le Moan N, et al. Suppression of oxidative stress by beta-hydroxybutyrate, an endogenous histone deacetylase inhibitor. Science. 2013;339(6116):211-4.

11. Furukawa S, Fujita T, Shimabukuro M, Iwaki M, Yamada Y, Nakajima Y, et al. Increased oxidative stress in obesity and its impact on metabolic syndrome. J Clin Invest. 2004;114(12):1752-61.

12. Holvoet P. Relations between metabolic syndrome, oxidative stress and inflammation and cardiovascular disease. Verh K Acad Geneeskd Belg. 2008;70(3):193-219.

13. Stubbs BJ, Cox PJ, Evans RD, Santer P, Miller JJ, Faull OK, et al. On the Metabolism of Exogenous Ketones in Humans. Front Physiol. 2017;8:848.

14. Kesl SL, Poff AM, Ward NP, Fiorelli TN, Ari C, Van Putten AJ, et al. Effects of exogenous ketone supplementation on blood ketone, glucose, triglyceride, and lipoprotein levels in Sprague-Dawley rats. Nutr Metab (Lond). 2016;13:9.

15. Feinman RD, Pogozelski WK, Astrup A, Bernstein RK, Fine EJ, Westman EC, et al. Dietary carbohydrate restriction as the first approach in diabetes management: critical review and evidence base. Nutrition. 2015;31(1):1-13.

16. Krebs HA. The regulation of the release of ketone bodies by the liver. Adv Enzyme Regul. 1966;4:339-54.

17. Cahill GF, Jr. Fuel metabolism in starvation. Annu Rev Nutr. 2006;26:1-22.

18. Di Lullo GA, Sweeney SM, Korkko J, Ala-Kokko L, San Antonio JD. Mapping the ligand-binding sites and disease-associated mutations on the most abundant protein in the human, type I collagen. J Biol Chem. 2002;277(6):4223-31.

19. Kitakaze T, Sakamoto T, Kitano T, Inoue N, Sugihara F, Harada N, et al. The collagen derived dipeptide hydroxyprolyl-glycine promotes C2C12 myoblast differentiation and myotube hypertrophy. Biochem Biophys Res Commun. 2016;478(3):1292-7.

20. Zdzieblik D, Oesser S, Baumstark MW, Gollhofer A, Konig D. Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcopenic men: a randomised controlled trial. Br J Nutr. 2015;114(8):1237-45.

21. Bruyere O, Zegels B, Leonori L, Rabenda V, Janssen A, Bourges C, et al. Effect of collagen hydrolysate in articular pain: a 6-month randomized, double-blind, placebo controlled study. Complement Ther Med. 2012;20(3):124-30.

22. Konig D, Oesser S, Scharla S, Zdzieblik D, Gollhofer A. Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women-A Randomized Controlled Study. Nutrients. 2018;10(1).

23. Proksch E, Segger D, Degwert J, Schunck M, Zague V, Oesser S. Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin Pharmacol Physiol. 2014;27(1):47-55.

24. Schunck M, Zague V, Oesser S, Proksch E. Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology. J Med Food. 2015;18(12):1340-8.

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