Apple Cider Vinegar

$24.99

Keywords: Metabolism, Fat burn, Energy Expenditure, Weight Loss and Maintenance, Healthy Blood Glucose and Cholesterol, Antioxidant, Detoxification and Cleansing

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Description

 

Keywords: Metabolism, Fat burn, Energy Expenditure, Weight Loss and Maintenance, Healthy Blood Glucose and Cholesterol, Antioxidant, Detoxification and Cleansing,

 

TET METABOLIC’s Apple cider vinegar+ Extra Natural Antioxidants, a blend of Apple Cider Vinegar, Aloe Vera Leaf, Astragalus Root, Cayenne Pepper, Coconut and Vitamin A is the complete metabolism booster.

Apple cider vinegar has several metabolic effects as shown in both human and animal studies. About 3 weeks of apple cider vinegar + supplementation reduced the average weight by 8.7 lb (5% of BMI) (1). Apple cider vinegar increases HDL-c, lowers blood TG and LDL-c (improves the blood cholesterol profile) (1, 2), reduces oxidative stress and the risk of obesity (3, 4). Apple cider vinegar is inferred to have an anti-obesogenic effect (4). It also serves as a detoxifying agent.

Experimental animals fed with diet mixed with vinegar burned more fat than the control animals on just the regular diet (5). Vinegar administration significantly reduces high HbA1c conditions (2, 6). Vinegar consumption with carbohydrate containing diet reduces the expected increase in blood glucose (7, 8) possibly by slowing the rate at which food leaves the stomach into the small intestines for absorption (gastric emptying)(9, 10). Additionally, vinegar consumption preserves the insulin-secreting pancreatic cells by improving insulin’s effectiveness (6, 8, 11). Vinegar intake also promotes satiety (11).

Aloe Vera

Aloe Vera is an anti-inflammatory agent and aids in the modulation of the immune system to fight off diseases (12).  Aloe Vera promotes whole-body insulin sensitivity and glucose tolerance as it promotes the reduction of high fasting glucose and HbA1c (13-15). It also improves blood cholesterol (triglycerides) profile (13-15).

Astragalus Root

For centuries, Astragalus has been an important component of Chinese traditional medicine, generally used to support the immune system. Some of the main active constituents of Astragalus root are the saponins and the flavonoids which have anti-inflammatory, immunostimulatory and antioxidative properties (16, 17). Astragalus root is also used to promote healthy blood sugar and cholesterol levels (17).

Cayenne Pepper

Some of the active components of Cayenne Pepper are capsaicin, phenols and flavonoids (18, 19). Capsaicin has pain-relieving properties (18) whiles Phenols and flavonoids are potent antioxidants (19).

Coconut

Coconut is rich in medium chain triglycerides (MCTs) (20, 21). MCTs increase energy expenditure (22, 23), stimulate fat burning, decrease fat storage (24), suppresses the urge to take in excess food (25, 26) and promote weight loss (27, 28).

Vitamin A

Vitamin A among its many important functions is regulation of fat accumulation/ formation (29-31). It suppresses obesity and improves insulin responsiveness (29).

Oxidative stress is central to the cause and complications of most chronic diseases (32). TET METABOLIC’s Apple Cider Vinegar + presents a rich blend of antioxidants from Vitamin A, Aloe Vera Leaf, Astragalus Root, Coconut, Cayenne Pepper and Apple Cider Vinegar itself (33-40). Antioxidants subdue the oxidative stress (41, 42). TET Metabolic’s Apple Cider Vinegar +  is also fitting for whole body cleanse.

Reference

  1. Balliett M, Burke JR. Changes in anthropometric measurements, body composition, blood pressure, lipid profile, and testosterone in patients participating in a low-energy dietary intervention. J Chiropr Med. 2013;12(1):3-14.
  2. Shishehbor F, Mansoori A, Sarkaki AR, Jalali MT, Latifi SM. Apple cider vinegar attenuates lipid profile in normal and diabetic rats. Pak J Biol Sci. 2008;11(23):2634-8.
  3. Halima BH, Sonia G, Sarra K, Houda BJ, Fethi BS, Abdallah A. Apple Cider Vinegar Attenuates Oxidative Stress and Reduces the Risk of Obesity in High-Fat-Fed Male Wistar Rats. J Med Food. 2018;21(1):70-80.
  4. Bouderbala H, Kaddouri H, Kheroua O, Saidi D. [Anti-obesogenic effect of apple cider vinegar in rats subjected to a high fat diet]. Ann Cardiol Angeiol (Paris). 2016;65(3):208-13.
  5. Ichikawa M, Ohta M, Kanai S, Yoshida Y, Takano S, Ueoka T, et al. Bitter melon malt vinegar increases daily energy turnover in rats. J Nutr Sci Vitaminol (Tokyo). 2003;49(6):428-33.
  6. Siddiqui FJ, Assam PN, de Souza NN, Sultana R, Dalan R, Chan ES. Diabetes Control: Is Vinegar a Promising Candidate to Help Achieve Targets? J Evid Based Integr Med. 2018;23:2156587217753004.
  7. Johnston CS, Steplewska I, Long CA, Harris LN, Ryals RH. Examination of the antiglycemic properties of vinegar in healthy adults. Ann Nutr Metab. 2010;56(1):74-9.
  8. Leeman M, Ostman E, Bjorck I. Vinegar dressing and cold storage of potatoes lowers postprandial glycaemic and insulinaemic responses in healthy subjects. Eur J Clin Nutr. 2005;59(11):1266-71.
  9. Liljeberg H, Bjorck I. Delayed gastric emptying rate may explain improved glycaemia in healthy subjects to a starchy meal with added vinegar. Eur J Clin Nutr. 1998;52(5):368-71.
  10. Johnston CS, Gaas CA. Vinegar: medicinal uses and antiglycemic effect. MedGenMed. 2006;8(2):61.
  11. Ostman E, Granfeldt Y, Persson L, Bjorck I. Vinegar supplementation lowers glucose and insulin responses and increases satiety after a bread meal in healthy subjects. Eur J Clin Nutr. 2005;59(9):983-8.
  12. Hutter JA, Salman M, Stavinoha WB, Satsangi N, Williams RF, Streeper RT, et al. Antiinflammatory C-glucosyl chromone from Aloe barbadensis. J Nat Prod. 1996;59(5):541-3.
  13. Vogler BK, Ernst E. Aloe vera: a systematic review of its clinical effectiveness. Br J Gen Pract. 1999;49(447):823-8.
  14. Devaraj S, Yimam M, Brownell LA, Jialal I, Singh S, Jia Q. Effects of Aloe vera supplementation in subjects with prediabetes/metabolic syndrome. Metab Syndr Relat Disord. 2013;11(1):35-40.
  15. Yongchaiyudha S, Rungpitarangsi V, Bunyapraphatsara N, Chokechaijaroenporn O. Antidiabetic activity of Aloe vera L. juice. I. Clinical trial in new cases of diabetes mellitus. Phytomedicine. 1996;3(3):241-3.
  16. Linnek J, Mitaine-Offer AC, Miyamoto T, Duchamp O, Mirjolet JF, Lacaille-Dubois MA. Cycloartane-type glycosides from two species of Astragalus (Fabaceae). Nat Prod Commun. 2009;4(4):477-8.
  17. Li X, Qu L, Dong Y, Han L, Liu E, Fang S, et al. A review of recent research progress on the astragalus genus. Molecules. 2014;19(11):18850-80.
  18. Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum annuum fruit powder, capsicum frutescens fruit, capsicum frutescens fruit extract, capsicum frutescens resin, and capsaicin. Int J Toxicol. 2007;26 Suppl 1:3-106.
  19. Yazdizadeh Shotorbani N, Jamei R, Heidari R. Antioxidant activities of two sweet pepper Capsicum annuum L. varieties phenolic extracts and the effects of thermal treatment. Avicenna J Phytomed. 2013;3(1):25-34.
  20. Kumar SN. Variability in coconut (Cocos nucifera L.) germplasm and hybrids for fatty acid profile of oil. J Agric Food Chem. 2011;59(24):13050-8.
  21. Mansor TST, Che Man, Y. B., Shuhaimi, M, Abdul Afiq, M. J. and Ku Nurul, F. K. M. . Physicochemical properties of virgin coconut oil extracted from different processing methods. International Food Research Journal 2012;19 (3):837-45.
  22. St-Onge MP, Ross R, Parsons WD, Jones PJ. Medium-chain triglycerides increase energy expenditure and decrease adiposity in overweight men. Obes Res. 2003;11(3):395-402.
  23. St-Onge MP, Bourque C, Jones PJ, Ross R, Parsons WE. Medium- versus long-chain triglycerides for 27 days increases fat oxidation and energy expenditure without resulting in changes in body composition in overweight women. Int J Obes Relat Metab Disord. 2003;27(1):95-102.
  24. St-Onge MP, Jones PJ. Greater rise in fat oxidation with medium-chain triglyceride consumption relative to long-chain triglyceride is associated with lower initial body weight and greater loss of subcutaneous adipose tissue. Int J Obes Relat Metab Disord. 2003;27(12):1565-71.
  25. Clegg ME. Medium-chain triglycerides are advantageous in promoting weight loss although not beneficial to exercise performance. Int J Food Sci Nutr. 2010;61(7):653-79.
  26. St-Onge MP, Mayrsohn B, O’Keeffe M, Kissileff HR, Choudhury AR, Laferrere B. Impact of medium and long chain triglycerides consumption on appetite and food intake in overweight men. Eur J Clin Nutr. 2014;68(10):1134-40.
  27. St-Onge MP, Bosarge A. Weight-loss diet that includes consumption of medium-chain triacylglycerol oil leads to a greater rate of weight and fat mass loss than does olive oil. Am J Clin Nutr. 2008;87(3):621-6.
  28. Tsuji H, Kasai M, Takeuchi H, Nakamura M, Okazaki M, Kondo K. Dietary medium-chain triacylglycerols suppress accumulation of body fat in a double-blind, controlled trial in healthy men and women. J Nutr. 2001;131(11):2853-9.
  29. Berry DC, Noy N. All-trans-retinoic acid represses obesity and insulin resistance by activating both peroxisome proliferation-activated receptor beta/delta and retinoic acid receptor. Mol Cell Biol. 2009;29(12):3286-96.
  30. Ziouzenkova O, Orasanu G, Sharlach M, Akiyama TE, Berger JP, Viereck J, et al. Retinaldehyde represses adipogenesis and diet-induced obesity. Nat Med. 2007;13(6):695-702.
  31. Zhang M, Hu P, Krois CR, Kane MA, Napoli JL. Altered vitamin A homeostasis and increased size and adiposity in the rdh1-null mouse. FASEB J. 2007;21(11):2886-96.
  32. Maritim AC, Sanders RA, Watkins JB, 3rd. Diabetes, oxidative stress, and antioxidants: a review. J Biochem Mol Toxicol. 2003;17(1):24-38.
  33. von Lintig J. Provitamin A metabolism and functions in mammalian biology. Am J Clin Nutr. 2012;96(5):1234S-44S.
  34. Demmig-Adams B, Adams WW, 3rd. Antioxidants in photosynthesis and human nutrition. Science. 2002;298(5601):2149-53.
  35. Yimam M, Brownell L, Jia Q. Aloesin as a medical food ingredient for systemic oxidative stress of diabetes. World J Diabetes. 2015;6(9):1097-107.
  36. Lee KY, Weintraub ST, Yu BP. Isolation and identification of a phenolic antioxidant from Aloe barbadensis. Free Radic Biol Med. 2000;28(2):261-5.
  37. Li XT, Zhang YK, Kuang HX, Jin FX, Liu DW, Gao MB, et al. Mitochondrial protection and anti-aging activity of Astragalus polysaccharides and their potential mechanism. Int J Mol Sci. 2012;13(2):1747-61.
  38. Marina AM, Man YB, Nazimah SA, Amin I. Antioxidant capacity and phenolic acids of virgin coconut oil. Int J Food Sci Nutr. 2009;60 Suppl 2:114-23.
  39. Otunola GA, Oloyede OB, Oladiji AT, Afolayan AJ. Selected spices and their combination modulate hypercholesterolemia-induced oxidative stress in experimental rats. Biol Res. 2014;47:5.
  40. Bae H, Jayaprakasha GK, Jifon J, Patil BS. Variation of antioxidant activity and the levels of bioactive compounds in lipophilic and hydrophilic extracts from hot pepper (Capsicum spp.) cultivars. Food Chem. 2012;134(4):1912-8.
  41. Bonnard C, Durand A, Peyrol S, Chanseaume E, Chauvin MA, Morio B, et al. Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant mice. J Clin Invest. 2008;118(2):789-800.
  42. Ikemura M, Nishikawa M, Hyoudou K, Kobayashi Y, Yamashita F, Hashida M. Improvement of insulin resistance by removal of systemic hydrogen peroxide by PEGylated catalase in obese mice. Mol Pharm. 2010;7(6):2069-76.

 

Product Information

Keywords : Metabolism, Fat burn, Energy Expenditure, Weight Loss and Maintenance, Healthy Blood Glucose and Cholesterol, Antioxidant, Detoxification and Cleansing

Supplement Fact

Product Literature

TET METABOLIC’s Apple cider vinegar+ Extra Natural Antioxidants, a blend of Apple Cider Vinegar, Aloe Vera Leaf, Astragalus Root, Cayenne Pepper, Coconut and Vitamin A is the complete metabolism booster.

Apple cider vinegar has several metabolic effects as shown in both human and animal studies. About 3 weeks of apple cider vinegar + supplementation reduced the average weight by 8.7 lb (5% of BMI) (1). Apple cider vinegar increases HDL-c, lowers blood TG and LDL-c (improves the blood cholesterol profile) (1, 2), reduces oxidative stress and the risk of obesity (3, 4). Apple cider vinegar is inferred to have an anti-obesogenic effect (4). It also serves as a detoxifying agent.

Experimental animals fed with diet mixed with vinegar burned more fat than the control animals on just the regular diet (5). Vinegar administration significantly reduces high HbA1c conditions (2, 6). Vinegar consumption with carbohydrate containing diet reduces the expected increase in blood glucose (7, 8) possibly by slowing the rate at which food leaves the stomach into the small intestines for absorption (gastric emptying)(9, 10). Additionally, vinegar consumption preserves the insulin-secreting pancreatic cells by improving insulin’s effectiveness (6, 8, 11). Vinegar intake also promotes satiety (11).

Aloe Vera

Aloe Vera is an anti-inflammatory agent and aids in the modulation of the immune system to fight off diseases (12).  Aloe Vera promotes whole-body insulin sensitivity and glucose tolerance as it promotes the reduction of high fasting glucose and HbA1c (13-15). It also improves blood cholesterol (triglycerides) profile (13-15).

Astragalus Root

For centuries, Astragalus has been an important component of Chinese traditional medicine, generally used to support the immune system. Some of the main active constituents of Astragalus root are the saponins and the flavonoids which have anti-inflammatory, immunostimulatory and antioxidative properties (16, 17). Astragalus root is also used to promote healthy blood sugar and cholesterol levels (17).

Cayenne Pepper

Some of the active components of Cayenne Pepper are capsaicin, phenols and flavonoids (18, 19). Capsaicin has pain-relieving properties (18) whiles Phenols and flavonoids are potent antioxidants (19).

Coconut

Coconut is rich in medium chain triglycerides (MCTs) (20, 21). MCTs increase energy expenditure (22, 23), stimulate fat burning, decrease fat storage (24), suppresses the urge to take in excess food (25, 26) and promote weight loss (27, 28).

Vitamin A

Vitamin A among its many important functions is regulation of fat accumulation/ formation (29-31). It suppresses obesity and improves insulin responsiveness (29).

Oxidative stress is central to the cause and complications of most chronic diseases (32). TET METABOLIC’s Apple Cider Vinegar + presents a rich blend of antioxidants from Vitamin A, Aloe Vera Leaf, Astragalus Root, Coconut, Cayenne Pepper and Apple Cider Vinegar itself (33-40). Antioxidants subdue the oxidative stress (41, 42). TET Metabolic’s Apple Cider Vinegar +  is also fitting for whole body cleanse.

Reference

  1. Balliett M, Burke JR. Changes in anthropometric measurements, body composition, blood pressure, lipid profile, and testosterone in patients participating in a low-energy dietary intervention. J Chiropr Med. 2013;12(1):3-14.
  2. Shishehbor F, Mansoori A, Sarkaki AR, Jalali MT, Latifi SM. Apple cider vinegar attenuates lipid profile in normal and diabetic rats. Pak J Biol Sci. 2008;11(23):2634-8.
  3. Halima BH, Sonia G, Sarra K, Houda BJ, Fethi BS, Abdallah A. Apple Cider Vinegar Attenuates Oxidative Stress and Reduces the Risk of Obesity in High-Fat-Fed Male Wistar Rats. J Med Food. 2018;21(1):70-80.
  4. Bouderbala H, Kaddouri H, Kheroua O, Saidi D. [Anti-obesogenic effect of apple cider vinegar in rats subjected to a high fat diet]. Ann Cardiol Angeiol (Paris). 2016;65(3):208-13.
  5. Ichikawa M, Ohta M, Kanai S, Yoshida Y, Takano S, Ueoka T, et al. Bitter melon malt vinegar increases daily energy turnover in rats. J Nutr Sci Vitaminol (Tokyo). 2003;49(6):428-33.
  6. Siddiqui FJ, Assam PN, de Souza NN, Sultana R, Dalan R, Chan ES. Diabetes Control: Is Vinegar a Promising Candidate to Help Achieve Targets? J Evid Based Integr Med. 2018;23:2156587217753004.
  7. Johnston CS, Steplewska I, Long CA, Harris LN, Ryals RH. Examination of the antiglycemic properties of vinegar in healthy adults. Ann Nutr Metab. 2010;56(1):74-9.
  8. Leeman M, Ostman E, Bjorck I. Vinegar dressing and cold storage of potatoes lowers postprandial glycaemic and insulinaemic responses in healthy subjects. Eur J Clin Nutr. 2005;59(11):1266-71.
  9. Liljeberg H, Bjorck I. Delayed gastric emptying rate may explain improved glycaemia in healthy subjects to a starchy meal with added vinegar. Eur J Clin Nutr. 1998;52(5):368-71.
  10. Johnston CS, Gaas CA. Vinegar: medicinal uses and antiglycemic effect. MedGenMed. 2006;8(2):61.
  11. Ostman E, Granfeldt Y, Persson L, Bjorck I. Vinegar supplementation lowers glucose and insulin responses and increases satiety after a bread meal in healthy subjects. Eur J Clin Nutr. 2005;59(9):983-8.
  12. Hutter JA, Salman M, Stavinoha WB, Satsangi N, Williams RF, Streeper RT, et al. Antiinflammatory C-glucosyl chromone from Aloe barbadensis. J Nat Prod. 1996;59(5):541-3.
  13. Vogler BK, Ernst E. Aloe vera: a systematic review of its clinical effectiveness. Br J Gen Pract. 1999;49(447):823-8.
  14. Devaraj S, Yimam M, Brownell LA, Jialal I, Singh S, Jia Q. Effects of Aloe vera supplementation in subjects with prediabetes/metabolic syndrome. Metab Syndr Relat Disord. 2013;11(1):35-40.
  15. Yongchaiyudha S, Rungpitarangsi V, Bunyapraphatsara N, Chokechaijaroenporn O. Antidiabetic activity of Aloe vera L. juice. I. Clinical trial in new cases of diabetes mellitus. Phytomedicine. 1996;3(3):241-3.
  16. Linnek J, Mitaine-Offer AC, Miyamoto T, Duchamp O, Mirjolet JF, Lacaille-Dubois MA. Cycloartane-type glycosides from two species of Astragalus (Fabaceae). Nat Prod Commun. 2009;4(4):477-8.
  17. Li X, Qu L, Dong Y, Han L, Liu E, Fang S, et al. A review of recent research progress on the astragalus genus. Molecules. 2014;19(11):18850-80.
  18. Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum annuum fruit powder, capsicum frutescens fruit, capsicum frutescens fruit extract, capsicum frutescens resin, and capsaicin. Int J Toxicol. 2007;26 Suppl 1:3-106.
  19. Yazdizadeh Shotorbani N, Jamei R, Heidari R. Antioxidant activities of two sweet pepper Capsicum annuum L. varieties phenolic extracts and the effects of thermal treatment. Avicenna J Phytomed. 2013;3(1):25-34.
  20. Kumar SN. Variability in coconut (Cocos nucifera L.) germplasm and hybrids for fatty acid profile of oil. J Agric Food Chem. 2011;59(24):13050-8.
  21. Mansor TST, Che Man, Y. B., Shuhaimi, M, Abdul Afiq, M. J. and Ku Nurul, F. K. M. . Physicochemical properties of virgin coconut oil extracted from different processing methods. International Food Research Journal 2012;19 (3):837-45.
  22. St-Onge MP, Ross R, Parsons WD, Jones PJ. Medium-chain triglycerides increase energy expenditure and decrease adiposity in overweight men. Obes Res. 2003;11(3):395-402.
  23. St-Onge MP, Bourque C, Jones PJ, Ross R, Parsons WE. Medium- versus long-chain triglycerides for 27 days increases fat oxidation and energy expenditure without resulting in changes in body composition in overweight women. Int J Obes Relat Metab Disord. 2003;27(1):95-102.
  24. St-Onge MP, Jones PJ. Greater rise in fat oxidation with medium-chain triglyceride consumption relative to long-chain triglyceride is associated with lower initial body weight and greater loss of subcutaneous adipose tissue. Int J Obes Relat Metab Disord. 2003;27(12):1565-71.
  25. Clegg ME. Medium-chain triglycerides are advantageous in promoting weight loss although not beneficial to exercise performance. Int J Food Sci Nutr. 2010;61(7):653-79.
  26. St-Onge MP, Mayrsohn B, O’Keeffe M, Kissileff HR, Choudhury AR, Laferrere B. Impact of medium and long chain triglycerides consumption on appetite and food intake in overweight men. Eur J Clin Nutr. 2014;68(10):1134-40.
  27. St-Onge MP, Bosarge A. Weight-loss diet that includes consumption of medium-chain triacylglycerol oil leads to a greater rate of weight and fat mass loss than does olive oil. Am J Clin Nutr. 2008;87(3):621-6.
  28. Tsuji H, Kasai M, Takeuchi H, Nakamura M, Okazaki M, Kondo K. Dietary medium-chain triacylglycerols suppress accumulation of body fat in a double-blind, controlled trial in healthy men and women. J Nutr. 2001;131(11):2853-9.
  29. Berry DC, Noy N. All-trans-retinoic acid represses obesity and insulin resistance by activating both peroxisome proliferation-activated receptor beta/delta and retinoic acid receptor. Mol Cell Biol. 2009;29(12):3286-96.
  30. Ziouzenkova O, Orasanu G, Sharlach M, Akiyama TE, Berger JP, Viereck J, et al. Retinaldehyde represses adipogenesis and diet-induced obesity. Nat Med. 2007;13(6):695-702.
  31. Zhang M, Hu P, Krois CR, Kane MA, Napoli JL. Altered vitamin A homeostasis and increased size and adiposity in the rdh1-null mouse. FASEB J. 2007;21(11):2886-96.
  32. Maritim AC, Sanders RA, Watkins JB, 3rd. Diabetes, oxidative stress, and antioxidants: a review. J Biochem Mol Toxicol. 2003;17(1):24-38.
  33. von Lintig J. Provitamin A metabolism and functions in mammalian biology. Am J Clin Nutr. 2012;96(5):1234S-44S.
  34. Demmig-Adams B, Adams WW, 3rd. Antioxidants in photosynthesis and human nutrition. Science. 2002;298(5601):2149-53.
  35. Yimam M, Brownell L, Jia Q. Aloesin as a medical food ingredient for systemic oxidative stress of diabetes. World J Diabetes. 2015;6(9):1097-107.
  36. Lee KY, Weintraub ST, Yu BP. Isolation and identification of a phenolic antioxidant from Aloe barbadensis. Free Radic Biol Med. 2000;28(2):261-5.
  37. Li XT, Zhang YK, Kuang HX, Jin FX, Liu DW, Gao MB, et al. Mitochondrial protection and anti-aging activity of Astragalus polysaccharides and their potential mechanism. Int J Mol Sci. 2012;13(2):1747-61.
  38. Marina AM, Man YB, Nazimah SA, Amin I. Antioxidant capacity and phenolic acids of virgin coconut oil. Int J Food Sci Nutr. 2009;60 Suppl 2:114-23.
  39. Otunola GA, Oloyede OB, Oladiji AT, Afolayan AJ. Selected spices and their combination modulate hypercholesterolemia-induced oxidative stress in experimental rats. Biol Res. 2014;47:5.
  40. Bae H, Jayaprakasha GK, Jifon J, Patil BS. Variation of antioxidant activity and the levels of bioactive compounds in lipophilic and hydrophilic extracts from hot pepper (Capsicum spp.) cultivars. Food Chem. 2012;134(4):1912-8.
  41. Bonnard C, Durand A, Peyrol S, Chanseaume E, Chauvin MA, Morio B, et al. Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant mice. J Clin Invest. 2008;118(2):789-800.
  42. Ikemura M, Nishikawa M, Hyoudou K, Kobayashi Y, Yamashita F, Hashida M. Improvement of insulin resistance by removal of systemic hydrogen peroxide by PEGylated catalase in obese mice. Mol Pharm. 2010;7(6):2069-76.

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